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Ankylosing spondylitis
Symptoms
Symptoms of Ankylosing spondylitis:
The most significant symptoms of AS are pain in lower back, painful stiffness
and immobility of back.
The totality of symptom may be described as under:
1. Fatigue associated with active inflammation
2. Pain and stiffness in the low back, upper buttock area , neck and the
remainder of the spine
3. Gradual onset of pain and it worsens progressively over months. Sometimes
rapid and intense onset
4. Pain and stiffness relieved by motion, heat and warm shower in morning.
5. Pain and stiffness are often worse in morning and after prolonged periods of
inactivity.
6. Patients with chronic condition can develop a complete bony fusion of spine.
Once fused, the pain in the spine disappears, but the patient has a complete
loss of spine mobility. These fused spines are particularly brittle and
vulnerable to breakage (fracture) when involved in trauma, such as motor vehicle
accidents.
7. Chronic spondylitis and ankylosis cause forward curvature of the upper torso
(thoracic spine), limiting breathing capacity.
8. Spondylitis can also affect areas where ribs attach to the upper spine,
further limiting lung capacity.
9. Ankylosing spondylitis can cause inflammation and scarring of the lungs,
causing coughing and shortness of breath, especially with exercise and
infections. Therefore, breathing difficulty can be a serious complication of
Ankylosing spondylitis. This is not very common, though.
10. Patients with Ankylosing spondylitis can also have arthritis in joints other
than the spine. Patients may notice pain, stiffness, heat, swelling, warmth,
and/or redness in joints such as the hips, knees, and ankles.
11. Some patients with this disease develop Achilles tendonitis, causing pain
and stiffness in the back of the heel, especially when pushing off with the foot
while walking up stairs. Inflammation of the tissues of the bottom of the foot,
plantar fascitis, occurs more frequently in people with Ankylosing spondylitis.
12. Patients with Ankylosing spondylitis can develop inflammation of the iris,
called iritis." Iritis is characterized by redness and pain in the eye,
especially when looking at bright lights. Recurrent attacks of iritis can affect
either eye.
13. In addition to the iris, the ciliary body and choroid of the eye can become
inflamed and this is referred to as uveitis.
14. Advanced spondylitis can lead to deposits of protein material called amyloid
into the kidneys and result in renal failure. Progressive renal disease can lead
to chronic fatigue and nausea and may require dialysis.
15. Since Ankylosing spondylitis often affects patients in adolescence, the
onset of low backache is sometimes incorrectly attributed to athletic injuries
in younger patients.
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