Ankylosing Spondylitis Conventional treatment

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b. Conventional medical treatment

The Conventional treatment of Ankylosing Spondylitis treats the disease condition with purpose of reducing inflammation and /or suppresses immunity.
Medications reduce inflammation in the spine and other joints and organs.
To reduce pain and stiffness conventional treatment uses Aspirin and other NSAIDS.

Commonly used NSAIDs (Non Steroidal Anti Inflammatory drugs)
• Indomethacin (indocin)
• Tolmetin (Tolectin)
• Sulindac (Clinoril)
• Naproxen (Naprosyn)
• Diclofenac (Voltaren)
 

The adverse effects of these medications are:
• Stomach upset
• Nausea
• Abdominal pain
• Diarrhea
• Sometimes bleeding ulcers
 

They advise to take these medicines with food in order to reduce side effects.
In advanced cases suffering from this disease they use even stronger medicines to suppress body’s immune system like:
1. Sulfasalazine (Azulfidine).
2. Methotrexate (Rheumatrex , Trexall)
3. Cortisone
4. Cyclosporin
5. TNF-α blockers
 

Some of the adverse effects of such medications:
1. Potential toxicity of liver which could lead to Cirrhosis.
2. Toxicity of bone marrow which could lead to anemia.